ZH Sem Bioinfo - Hans-Joachim Ruschewey

Taxonomic profiling of metagenomes from diverse environments with mOTUs3

Abstract Taxonomic profiling is a crucial task in microbiome research that aims at detecting and quantifying the relative abundance of microbes in biological samples. However, in many environments, varying fractions of microbial species still lack a sequenced genome and remain unaccounted for during taxonomic profiling based on shotgun metagenomic data. We present mOTUs3, a software tool which uses phylogenetic marker genes to profile metagenomes for 33.5k species-level operational taxonomic units, two thirds of which are currently not represented by sequenced genomes.

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@mbaudis 2021-12-16
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