ZH Seminars Bioinformatics - David Lyon

“aGOtool” protein centric functional enrichment

Abstract Doubtless there are GO terms in your enrichment analysis you shouldn’t see. Mass Spectrometry based shotgun-proteomics is inherently biased towards abundant proteins. This bias can influence GO-term enrichment analysis by showing enriched terms for abundant rather than e.g. post-translationally-modified (PTM) proteins. We have developed a method to correct for this bias and a freely accessible web-tool agotool.sund.ku.dk to facilitate the use for the scientific community. Now, after an eternity has passed, we are back and in the process to overhaul and expand this tool to satisfy a user near you.

@mbaudis 2019-06-12
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